This medicine should be used with caution when dimenhydrinate is given in conjunction with certain antibiotics which may cause ototoxicity. Dimenhydrinate may impair mental alertness required for the performance of potentially hazardous activities such as driving a vehicle or operating machinery.
Patient should also avoid alcoholic beverages while taking medication containing dimenhydrinate.
It should not be used in the presence of asthma, glaucoma, or enlargement of the prostate gland, except on advice of a physician.